Birds must not be slaughtered for human consumption during treatment.
Chickens may be slaughtered for human consumption only after 2 days from the last treatment. Nil withdrawal period for eggs.
Turkeys may be slaughtered for human consumption only after 5 days from the last treatment.
Do not use in birds hypersensitive to the active ingredient. Birds should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with Denagard 12.5% Solution. Severe growth depression or death may result. Concomitant use of tiamulin and the ionophore anticoccidal maduramicin may lead to a mild to moderate growth depression in chickens. The situation is transient and recovery normally occurs within 3-5 days following withdrawal of tiamulin treatment. This does not seem to occur with the ionophores lasalocid or semduramicin.
In order to avoid interactions between tiamulin and the incompatible ionophores monensin, narasin and salinomycin, the feed mill supplying the feed should be notified that tiamulin will be used and that these products should not be included in the feed or contaminate the feed. The feed should be tested for the ionophores prior to use if there is any suspicion that contamination of the feed might occur. If an interaction does occur, stop tiamulin water medication immediately and replace with fresh water. Remove contaminated feed as soon as possible and replace with feed not containing the tiamulin-incompatible ionophores.
When mixing, direct contact with the skin and eyes should be avoided by wearing impermeable rubber gloves and safety glasses.
In case of accidental eye contact, irrigate the eyes thoroughly with clean running water immediately. Seek medical advice if irritation persists.
Contaminated clothing should be removed and any splashes on to the skin should be washed off immediately.
Wash hands after use.
Pregnancy and Lactation:
Denagard is suitable for use in laying and breeding birds as it has been shown to have no adverse effects on egg production, fertility and hatchability in chickens and turkeys.
Fresh medicated water must be prepared every 24 hours. Watering equipment should be thoroughly cleaned prior to addition of Denagard 12.5% Solution. Do not store above 25°C.
For use in drinking water of chickens and turkeys only.
- Monitor water intake at frequent intervals during medication.
- If there is no response to treatment within five days, the diagnosis should be re-established.
- Water intake may be depressed during the administration of tiamulin to birds. It appears to be concentration dependent with 0.025% tiamulin reducing intake by approximately 15%.
It does not appear to have any adverse effect on overall performance of the birds or efficacy of the product.