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Tiamutin® 80% Premix (UK)

A free-flowing medicated feed premix, each kg containing 800g tiamulin hydrogen fumarate.
 

For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium spp. and Bacteroides spp. As an aid in the control of the enzootic pneumonia complex in pigs.

Dosage and Administration

For the treatment of clinical swine dysentery:
The dose is 5mg tiamulin hydrogen fumarate per kg bodyweight daily, administered for 7 to 10 days.
 

An inclusion rate of 125g Tiamutin 80% Premix (equivalent to 100g tiamulin hydrogen fumarate) per 1 tonne of feed should provide this dose in growing pigs.
 

Following recovery, continue medication at the preventive level to prevent recurrence of the disease.
 

For the control and prevention of swine dysentery:
The dose is 1.5-2mg tiamulin hydrogen fumarate per kg bodyweight, administered throughout the period of risk to control re-infection.
 

An inclusion rate of 37.5-50g Tiamutin 80% Premix (equivalent to 30-40g tiamulin hydrogen fumarate) per 1 tonne of feed should provide this dose in growing pigs. Feed throughout the period of risk to control re-infection.
 

As an aid in the control of enzootic pneumonia
complex in pigs:

The dose is 1.5-2mg tiamulin hydrogen fumarate per kg bodyweight daily administered for up to two months during the period of risk.
 

An inclusion rate of 37.5-50g Tiamutin 80% Premix (equivalent to 30-40g tiamulin hydrogen fumarate) per 1 tonne of feed should provide this dose in growing pigs.

Inclusion rates:

When medicating larger pigs including breeding animals or where inappetence occurs, the inclusion level may need adjusting as follows to give the correct dose.
 

Example: Dose - 5 mg tiamulin hydrogen fumarate per kg bodyweight
 

 
 

Average pig bodyweight (kg) x 5mg
Average daily feed intake (kg)
=
g tiamulin hydrogen
fumarate per tonne feed

 
 

Dose - 2mg tiamulin hydrogen fumarate per kg bodyweight
 

 
 

Average pig bodyweight (kg) x 2mg
Average daily feed intake (kg)
=
g tiamulin hydrogen
fumarate per tonne feed

 
 

When mixing small quantities e.g. 37.5, 50 or 125g per tonne, it is advisable to handmix the required amount of Premix into approximately 20 kg of feed or feed supplement prior to mixing into the complete feed.

Contra-indications, warnings, etc.

Warnings:
Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after 24 hours from the last treatment.
 

Contra-indications:
Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with tiamulin hydrogen fumarate at the 100g per tonne (equivalent to 5mg/kg bodyweight daily dose). Severe growth depression or death may result.
 

Interaction has been observed between tiamulin hydrogen fumarate at 30-40g per tonne of feed and narasin at 70g per tonne of feed.
 

Operator Warnings:
When mixing, direct contact with the skin and mucous membranes should be avoided.
 

Pharmaceutical Warnings:
Do not store above 25°C. Store in a dry place. Protect from light.
 

To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed ingredients before incorporation in the final mix.
 

The product will remain stable in the finished feed or vitamin/mineral premixes for 3 months.
 

Precautions:
To be used in pig rations only.
 

On rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin hydrogen fumarate.
 

If there is no response to treatment within 5 days, the diagnosis should be re-established.
 

Severely affected pigs showing inappetence should be medicated with Tiamutin 12.5% Solution or Tiamutin 200 Injection.
 

Further Information:
Studies have shown that 30-40g per tonne of feed tiamulin hydrogen fumarate in the feed will reduce production losses associated with enzootic pneumonia. A reduction in clinical disease incidence or severity may not necessarily be seen. Attention should be paid to ventilation and stocking density in conjunction with medication. If this product is incorporated in an intermediate feeding stuff, care should be taken to ensure that the intermediate feeding stuff is incorporated at a rate which will yield the same concentration of active ingredient in the final feed as stated in the Medicated Feedingstuffs (MFS) Prescription.
 

The product is compatible with recommended doses of chlortetracycline and tylosin.
 

Studies have shown that at tiamulin hydrogen fumarate inclusion levels of 30-40g per tonne (equivalent to 1.5-2.0mg/kg bodyweight daily) no interaction occurs with salinomycin at 60g per tonne in the feed or monensin at 100g per tonne in the feed.
 

Disposal:
Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.
 

Keep out of reach of children.
 

For animal treatment only.
 

® Registered trademark of Novartis AG, Basel, Switzerland.

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