Groups of five pigs received drinking water medicated with tiamulin hydrogen fumarate at levels of 60ppm, 120ppm and 180ppm for five consecutive days. (Trials by Anderson M.D. and others [?])
On the last day of medication the pigs were killed and the tissues harvested for microbiological assay. The results of the assays are shown below.
| USA |
Anderson, M.D. and others (1994) |
Water
inclusion
level |
Calculated
daily
dosage (thf)
(mg/kg)
|
Tiamulin activity (μg/g)
|
|
Lung
|
Tonsils
|
Colon
mucosa
|
Colon
contents
|
| 60ppm |
6.2
|
1.11
|
a
|
a
|
2.16
|
| 120ppm |
13.2
|
4.26
|
a
|
1.56
|
5.59
|
| 180ppm |
20.9
|
8.5
|
2.5
|
3.39
|
18.58
|
|
| 
