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Colitis - trial data

Trial data - Porcine Colonic Spirochaetosis (PCS, Colitis)

Trial by Glossop, Edwards and Cobb (2000)

Glossop, Edwards and Cobb (2000) [?] in UK reported to Novartis Animal Health on the results of a study with Denagard® Premix to treat and control PCS infection. A level of 100 ppm tiamulin hydrogen fumarate was used for a trial period of 12 consecutive days.
 

There were major benefits in productivity (average daily gain and feed conversion efficiency) recorded for the Denagard medicated group compared to the unmedicated, infected control group, as shown below:
 


 

Glossop, Edwards and Cobb (2000)
Denagard® (tiamulin) productivity improvements
  Infected non-medicated group (172 pigs) Infected Denagard medicated group (168 pigs) Index P-value
Average daily gain (g) (days -1 to +11) 440 515 17.0% imp. 0.001
Feed conversion efficiency (days -1 to +11) 2.08 1.88 10% imp. 0.135

 

Trial by Glossop, C. (2004)

Glossop determined the effect of Denagard® premix in the treatment of a naturally occurring colitis infection in growers. Denagard improved significantly at a level of 5mg/kg bw the clinical condition of pigs and prevented weight gain depression.

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