Colitis is being increasingly recognised as an economically significant diarrhoeal disease in weaners/growers, less common in finishing pigs, which occurs either alone or in combination with enteric pathogens such as L.i., the causative agent of Porcine Proliferative Enteropathy (PPE, ileitis).
Colitis and Ileitis are now known to occur concomitantly with the post-weaning multi-systemic wasting syndrome (PMWS) associated with PCV-2 virus infection.
Colitis (Porcine Colonic Spirochaetosis, PCS) is a non-fatal, diarrhoeal disease of growing pigs caused by the weakly beta-haemolytic spirochaete, B. pilosicoli. The disease is present in all types of farms world-wide, regardless of management and hygiene practices. Clinically PCS is typically seen 10 - 14 days after pigs with different health status are moved from the nursery to the grower facility, where they are mixed and fed a grower ration. [?]
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Colitis diarrhoea
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It is particularly common in countries (e.g. EU) where antibiotic growth promoters have been removed from the feed. Concurrent infections of B.p. with other pathogens such as Lawsonia intracellularis,
B. hyo and Salmonella are common. [ ?] They account for persistent problems accompanied by more severe reductions in growth performance and increased mortality. [ ?] B.p. organisms are not degraded within macrophage cells [ ?] and hence any effective treatments must reach B.p. within these cells. B.p. is highly susceptible to Tiamutin and Tiamutin is active intracellularly.
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